Pseudorabies (PRV), also known as Aujeszky’s disease
Pseudorabies (PRV), also known as Aujeszky’s disease
PRV, also known as suid herpesvirus-1 (SHV-1), is a contagious disease primarily affecting pigs, its natural host, though it can infect many other mammals (e.g., cattle, sheep, dogs, and cats). The virus targets the central nervous system and other organs. PRV establishes lifelong latent infection in pigs, similar to other herpesviruses. Although animals may recover clinically and appear healthy, the virus persists in a dormant state within the body. During periods of stress, it can reactivate (recrudescence), leading to renewed viral shedding and potential spread. Because of this, once swine have been identified as actively infected or a latent carrier, they are depopulated. In the United States, PRV is a reportable disease.
